Zerumbone increases oxidative stress in a thiol-dependent ROS-independent manner to increase DNA damage and sensitize colorectal cancer cells to radiation

Locally advanced rectal cancers are treated with neoadjuvant chemoradiation therapy followed by surgery. In a minority (∽20%) of patients, no tumor is present at the time of surgery; these patients with a complete pathologic response (pathCR) to neoadjuvant therapy have better treatment outcomes. Un...

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Detalles Bibliográficos
Autores principales: Deorukhkar, Amit, Ahuja, Niharika, Mercado, Armando-Lopez, Diagaradjane, Parmeswaran, Raju, Uma, Patel, Nalini, Mohindra, Pranshu, Diep, Nga, Guha, Sushovan, Krishnan, Sunil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329011/
https://www.ncbi.nlm.nih.gov/pubmed/25450478
http://dx.doi.org/10.1002/cam4.367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329011/
https://www.ncbi.nlm.nih.gov/pubmed/25450478
http://dx.doi.org/10.1002/cam4.367

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