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Combining capillary electrophoresis and next-generation sequencing for aptamer selection

Next-generation sequencing (NGS) machines can sequence millions of DNA strands in a single run, such as oligonucleotide (oligo) libraries comprising millions to trillions of discrete oligo sequences. Capillary electrophoresis is an attractive technique to select tight binding oligos or “aptamers” be...

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Detalles Bibliográficos
Autores principales: Riley, Kathryn R., Gagliano, Jason, Xiao, Jiajie, Libby, Kara, Saito, Shingo, Yu, Guo, Cubicciotti, Roger, Macosko, Jed, Colyer, Christa L., Guthold, Martin, Bonin, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329186/
https://www.ncbi.nlm.nih.gov/pubmed/25579462
http://dx.doi.org/10.1007/s00216-014-8427-y