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The case of triethylammonium cation loss during purification of certain nucleotide analogues: a cautionary note
Nucleotides, their analogues, and other phosphate esters and phosphoramidates often contain the triethylammonium cation as a counterion. We found that this may be lost during chromatographic purification or concentration of solutions, yielding products in acidic forms or containing sub-stoichiometri...
Autores principales: | Kolodziej, Krystian, Romanowska, Joanna, Stawinski, Jacek, Kraszewski, Adam, Sobkowski, Michal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329187/ https://www.ncbi.nlm.nih.gov/pubmed/25542580 http://dx.doi.org/10.1007/s00216-014-8397-0 |
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