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The role of individual caspases in cell death induction by taxanes in breast cancer cells

BACKGROUND: In previous study we showed that caspase-2 plays the role of an apical caspase in cell death induction by taxanes in breast cancer cells. This study deals with the role of other caspases. We tested breast cancer cell lines SK-BR-3 (functional caspase-3) and MCF-7 (nonfunctional caspase-3...

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Detalles Bibliográficos
Autores principales: Jelínek, Michael, Balušíková, Kamila, Schmiedlová, Martina, Němcová-Fürstová, Vlasta, Šrámek, Jan, Stančíková, Jitka, Zanardi, Ilaria, Ojima, Iwao, Kovář, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329194/
https://www.ncbi.nlm.nih.gov/pubmed/25685064
http://dx.doi.org/10.1186/s12935-015-0155-7