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Antioxidant polyphenol-rich extracts from the medicinal plants Antirhea borbonica, Doratoxylon apetalum and Gouania mauritiana protect 3T3-L1 preadipocytes against H(2)O(2), TNFα and LPS inflammatory mediators by regulating the expression of superoxide dismutase and NF-κB genes
BACKGROUND: Adipose cells responsible for fat storage are the targets of reactive oxygen species (ROS) like H(2)O(2) and pro-inflammatory agents including TNFα and LPS. Such mediators contribute to oxidative stress and alter inflammatory processes in adipose tissue, leading to insulin resistance dur...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329220/ https://www.ncbi.nlm.nih.gov/pubmed/25685071 http://dx.doi.org/10.1186/s12950-015-0055-6 |