Antioxidant polyphenol-rich extracts from the medicinal plants Antirhea borbonica, Doratoxylon apetalum and Gouania mauritiana protect 3T3-L1 preadipocytes against H(2)O(2), TNFα and LPS inflammatory mediators by regulating the expression of superoxide dismutase and NF-κB genes

BACKGROUND: Adipose cells responsible for fat storage are the targets of reactive oxygen species (ROS) like H(2)O(2) and pro-inflammatory agents including TNFα and LPS. Such mediators contribute to oxidative stress and alter inflammatory processes in adipose tissue, leading to insulin resistance dur...

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Detalles Bibliográficos
Autores principales: Marimoutou, Méry, Le Sage, Fanny, Smadja, Jacqueline, Lefebvre d’Hellencourt, Christian, Gonthier, Marie-Paule, Robert-Da Silva, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329220/
https://www.ncbi.nlm.nih.gov/pubmed/25685071
http://dx.doi.org/10.1186/s12950-015-0055-6

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