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Invited Review: Decoding the pathophysiological mechanisms that underlie RNA dysregulation in neurodegenerative disorders: a review of the current state of the art

Altered RNA metabolism is a key pathophysiological component causing several neurodegenerative diseases. Genetic mutations causing neurodegeneration occur in coding and noncoding regions of seemingly unrelated genes whose products do not always contribute to the gene expression process. Several path...

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Detalles Bibliográficos
Autores principales: Walsh, M J, Cooper-Knock, J, Dodd, J E, Stopford, M J, Mihaylov, S R, Kirby, J, Shaw, P J, Hautbergue, G M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329338/
https://www.ncbi.nlm.nih.gov/pubmed/25319671
http://dx.doi.org/10.1111/nan.12187