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Targeted Antiangiogenesis Gene Therapy Using Targeted Cationic Microbubbles Conjugated with CD105 Antibody Compared with Untargeted Cationic and Neutral Microbubbles

Objective This study aimed to develop targeted cationic microbubbles conjugated with a CD105 antibody (CMB105) for use in targeted vascular endothelial cell gene therapy and ultrasound imaging. We compared the results with untargeted cationic microbubbles (CMB) and neutral microbubbles (NMB). Method...

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Detalles Bibliográficos
Autores principales: Zhou, Yu, Gu, Haitao, Xu, Yan, Li, Fan, Kuang, Shaojing, Wang, Zhigang, Zhou, Xiyuan, Ma, Huafeng, Li, Pan, Zheng, Yuanyi, Ran, Haitao, Jian, Jia, Zhao, Yajing, Song, Weixiang, Wang, Qiushi, Wang, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329503/
https://www.ncbi.nlm.nih.gov/pubmed/25699099
http://dx.doi.org/10.7150/thno.10351