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Directed evolution induces tributyrin hydrolysis in a virulence factor of Xylella fastidiosa using a duplicated gene as a template

Duplication of genes is one of the preferred ways for natural selection to add advantageous functionality to the genome without having to reinvent the wheel with respect to catalytic efficiency and protein stability. The duplicated secretory virulence factors of Xylella fastidiosa (LesA, LesB and Le...

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Detalles Bibliográficos
Autores principales: Gouran, Hossein, Chakraborty, Sandeep, Rao, Basuthkar J., Asgeirsson, Bjarni, Dandekar, Abhaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329599/
https://www.ncbi.nlm.nih.gov/pubmed/25717364
http://dx.doi.org/10.12688/f1000research.5147.1