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CXCL13 antibody for the treatment of autoimmune disorders

BACKGROUND: Homeostatic B Cell-Attracting chemokine 1 (BCA-1) otherwise known as CXCL13 is constitutively expressed in secondary lymphoid organs by follicular dendritic cells (FDC) and macrophages. It is the only known ligand for the CXCR5 receptor, which is expressed on mature B cells, follicular h...

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Detalles Bibliográficos
Autores principales: Klimatcheva, Ekaterina, Pandina, Tracy, Reilly, Christine, Torno, Sebold, Bussler, Holm, Scrivens, Maria, Jonason, Alan, Mallow, Crystal, Doherty, Michael, Paris, Mark, Smith, Ernest S, Zauderer, Maurice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329654/
https://www.ncbi.nlm.nih.gov/pubmed/25879435
http://dx.doi.org/10.1186/s12865-015-0068-1