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Neuraminidase Inhibition Primes Short-Term Depression and Suppresses Long-Term Potentiation of Synaptic Transmission in the Rat Hippocampus

Neuraminidase (NEU) is a key enzyme that cleaves negatively charged sialic acid residues from membrane proteins and lipids. Clinical and basic science studies have shown that an imbalance in NEU metabolism or changes in NEU activity due to various pathological conditions parallel with behavior and c...

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Detalles Bibliográficos
Autores principales: Savotchenko, Alina, Romanov, Arthur, Isaev, Dmytro, Maximyuk, Oleksandr, Sydorenko, Vadym, Holmes, Gregory L., Isaeva, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329761/
https://www.ncbi.nlm.nih.gov/pubmed/25802763
http://dx.doi.org/10.1155/2015/908190