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From the Biology of PP2A to the PADs for Therapy of Hematologic Malignancies

Over the past decades, an emerging role of phosphatases in the pathogenesis of hematologic malignancies and solid tumors has been established. The tumor-suppressor protein phosphatase 2A (PP2A) belongs to the serine–threonine phosphatases family and accounts for the majority of serine–threonine phos...

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Detalles Bibliográficos
Autores principales: Ciccone, Maria, Calin, George A., Perrotti, Danilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329809/
https://www.ncbi.nlm.nih.gov/pubmed/25763353
http://dx.doi.org/10.3389/fonc.2015.00021