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Epigenetics and autoimmune diseases: the X chromosome-nucleolus nexus
Autoimmune diseases occur more often in females, suggesting a key role for the X chromosome. X chromosome inactivation, a major epigenetic feature in female cells that provides dosage compensation of X-linked genes to avoid overexpression, presents special vulnerabilities that can contribute to the...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329817/ https://www.ncbi.nlm.nih.gov/pubmed/25763008 http://dx.doi.org/10.3389/fgene.2015.00022 |