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Borreliacidal activity of Borrelia metal transporter A (BmtA) binding small molecules by manganese transport inhibition
Borrelia burgdorferi, the causative agent of Lyme disease, utilizes manganese (Mn) for its various metabolic needs. We hypothesized that blocking Mn transporter could be a possible approach to inhibit metabolic activity of this pathogen and eliminate the infection. We used a combination of in silico...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330029/ https://www.ncbi.nlm.nih.gov/pubmed/25709405 http://dx.doi.org/10.2147/DDDT.S77063 |