Development of lovastatin-loaded poly(lactic acid) microspheres for sustained oral delivery: in vitro and ex vivo evaluation

BACKGROUND: A novel lovastatin (LVT)-loaded poly(lactic acid) microsphere suitable for oral administration was developed in this study, and in vitro and in vivo characteristics were evaluated. METHODS: The designed microspheres were obtained by an improved emulsion-solvent evaporation method. The mo...

Descripción completa

Detalles Bibliográficos
Autores principales: Guan, Qigang, Chen, Wei, Hu, Xianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330030/
https://www.ncbi.nlm.nih.gov/pubmed/25709403
http://dx.doi.org/10.2147/DDDT.S76676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330030/
https://www.ncbi.nlm.nih.gov/pubmed/25709403
http://dx.doi.org/10.2147/DDDT.S76676

Ejemplares similares