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Development of lovastatin-loaded poly(lactic acid) microspheres for sustained oral delivery: in vitro and ex vivo evaluation

BACKGROUND: A novel lovastatin (LVT)-loaded poly(lactic acid) microsphere suitable for oral administration was developed in this study, and in vitro and in vivo characteristics were evaluated. METHODS: The designed microspheres were obtained by an improved emulsion-solvent evaporation method. The mo...

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Detalles Bibliográficos
Autores principales:	Guan, Qigang, Chen, Wei, Hu, Xianming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330030/ https://www.ncbi.nlm.nih.gov/pubmed/25709403 http://dx.doi.org/10.2147/DDDT.S76676

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