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Understanding Epistatic Interactions between Genes Targeted by Non-coding Regulatory Elements in Complex Diseases

Genome-wide association studies have proven the highly polygenic architecture of complex diseases or traits; therefore, single-locus-based methods are usually unable to detect all involved loci, especially when individual loci exert small effects. Moreover, the majority of associated single-nucleoti...

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Detalles Bibliográficos
Autores principales: Sung, Min Kyung, Bang, Hyoeun, Choi, Jung Kyoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Genome Organization 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330252/
https://www.ncbi.nlm.nih.gov/pubmed/25705156
http://dx.doi.org/10.5808/GI.2014.12.4.181