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Understanding Epistatic Interactions between Genes Targeted by Non-coding Regulatory Elements in Complex Diseases
Genome-wide association studies have proven the highly polygenic architecture of complex diseases or traits; therefore, single-locus-based methods are usually unable to detect all involved loci, especially when individual loci exert small effects. Moreover, the majority of associated single-nucleoti...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Korea Genome Organization
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330252/ https://www.ncbi.nlm.nih.gov/pubmed/25705156 http://dx.doi.org/10.5808/GI.2014.12.4.181 |