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HiTSelect: a comprehensive tool for high-complexity-pooled screen analysis

Genetic screens of an unprecedented scale have recently been made possible by the availability of high-complexity libraries of synthetic oligonucleotides designed to mediate either gene knockdown or gene knockout, coupled with next-generation sequencing. However, several sources of random noise and...

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Detalles Bibliográficos
Autores principales: Diaz, Aaron A., Qin, Han, Ramalho-Santos, Miguel, Song, Jun S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330337/
https://www.ncbi.nlm.nih.gov/pubmed/25428347
http://dx.doi.org/10.1093/nar/gku1197