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HiTSelect: a comprehensive tool for high-complexity-pooled screen analysis
Genetic screens of an unprecedented scale have recently been made possible by the availability of high-complexity libraries of synthetic oligonucleotides designed to mediate either gene knockdown or gene knockout, coupled with next-generation sequencing. However, several sources of random noise and...
Autores principales: | Diaz, Aaron A., Qin, Han, Ramalho-Santos, Miguel, Song, Jun S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330337/ https://www.ncbi.nlm.nih.gov/pubmed/25428347 http://dx.doi.org/10.1093/nar/gku1197 |
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