Targeting non-coding RNAs with the CRISPR/Cas9 system in human cell lines

The CRISPR/Cas has been recently shown to be a powerful genome-editing tool in a variety of organisms. However, these studies are mainly focused on protein-coding genes. The present study aims to determine whether this technology can be applied to non-coding genes. One of the challenges for knockout...

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Detalles Bibliográficos
Autores principales: Ho, Tsui-Ting, Zhou, Nanjiang, Huang, Jianguo, Koirala, Pratirodh, Xu, Min, Fung, Roland, Wu, Fangting, Mo, Yin-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330338/
https://www.ncbi.nlm.nih.gov/pubmed/25414344
http://dx.doi.org/10.1093/nar/gku1198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330338/
https://www.ncbi.nlm.nih.gov/pubmed/25414344
http://dx.doi.org/10.1093/nar/gku1198

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