Sparse expression bases in cancer reveal tumor drivers

We define a new category of candidate tumor drivers in cancer genome evolution: ‘selected expression regulators’ (SERs)—genes driving dysregulated transcriptional programs in cancer evolution. The SERs are identified from genome-wide tumor expression data with a novel method, namely SPARROW (SPARse...

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Detalles Bibliográficos
Autores principales: Logsdon, Benjamin A., Gentles, Andrew J., Miller, Chris P., Blau, C. Anthony, Becker, Pamela S., Lee, Su-In
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330344/
https://www.ncbi.nlm.nih.gov/pubmed/25583238
http://dx.doi.org/10.1093/nar/gku1290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330344/
https://www.ncbi.nlm.nih.gov/pubmed/25583238
http://dx.doi.org/10.1093/nar/gku1290

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