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Sparse expression bases in cancer reveal tumor drivers
We define a new category of candidate tumor drivers in cancer genome evolution: ‘selected expression regulators’ (SERs)—genes driving dysregulated transcriptional programs in cancer evolution. The SERs are identified from genome-wide tumor expression data with a novel method, namely SPARROW (SPARse...
Autores principales: | Logsdon, Benjamin A., Gentles, Andrew J., Miller, Chris P., Blau, C. Anthony, Becker, Pamela S., Lee, Su-In |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330344/ https://www.ncbi.nlm.nih.gov/pubmed/25583238 http://dx.doi.org/10.1093/nar/gku1290 |
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