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Function of the N-terminal segment of the RecA-dependent nuclease Ref

The bacteriophage P1 Ref (recombination enhancement function) protein is a RecA-dependent, HNH endonuclease. It can be directed to create targeted double-strand breaks within a displacement loop formed by RecA. The 76 amino acid N-terminal region of Ref is positively charged (25/76 amino acid residu...

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Detalles Bibliográficos
Autores principales: Gruber, Angela J., Olsen, Tayla M., Dvorak, Rachel H., Cox, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330346/
https://www.ncbi.nlm.nih.gov/pubmed/25618854
http://dx.doi.org/10.1093/nar/gku1330