Cargando…

Function of the N-terminal segment of the RecA-dependent nuclease Ref

The bacteriophage P1 Ref (recombination enhancement function) protein is a RecA-dependent, HNH endonuclease. It can be directed to create targeted double-strand breaks within a displacement loop formed by RecA. The 76 amino acid N-terminal region of Ref is positively charged (25/76 amino acid residu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gruber, Angela J., Olsen, Tayla M., Dvorak, Rachel H., Cox, Michael M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330346/ https://www.ncbi.nlm.nih.gov/pubmed/25618854 http://dx.doi.org/10.1093/nar/gku1330

Ejemplares similares

RecA-dependent programmable endonuclease Ref cleaves DNA in two distinct steps
por: Ronayne, Erin A., et al.
Publicado: (2014)

Changes in the tension in dsDNA alter the conformation of RecA bound to dsDNA–RecA filaments
por: Conover, Alyson J., et al.
Publicado: (2011)

Active displacement of RecA filaments by UvrD translocase activity
por: Petrova, Vessela, et al.
Publicado: (2015)

RadD is a RecA-dependent accessory protein that accelerates DNA strand exchange
por: Bonde, Nina J, et al.
Publicado: (2022)

Nonfilament-forming RecA dimer catalyzes homologous joint formation
por: Shinohara, Takeshi, et al.
Publicado: (2018)

High fidelity of RecA-catalyzed recombination: a watchdog of genetic diversity
por: Sagi, Dror, et al.
Publicado: (2006)

RecA homology search is promoted by mechanical stress along the scanned duplex DNA
por: Danilowicz, Claudia, et al.
Publicado: (2012)

Tracking in atomic detail the functional specializations in viral RecA helicases that occur during evolution
por: El Omari, Kamel, et al.
Publicado: (2013)

Complementary strand relocation may play vital roles in RecA-based homology recognition
por: Peacock-Villada, Alexandra, et al.
Publicado: (2012)

Single-molecule studies of the stringency factors and rates governing the polymerization of RecA on double-stranded DNA
por: Feinstein, Efraim, et al.
Publicado: (2011)

RecA requires two molecules of Mg(2+) ions for its optimal strand exchange activity in vitro
por: Kim, Raeyeong, et al.
Publicado: (2018)

Small-molecule sensitization of RecBCD helicase–nuclease to a Chi hotspot-activated state
por: Karabulut, Ahmet C, et al.
Publicado: (2020)

RecF protein targeting to postreplication (daughter strand) gaps I: DNA binding by RecF and RecFR
por: Henry, Camille, et al.
Publicado: (2023)

RecA can stimulate the relaxation activity of topoisomerase I: Molecular basis of topoisomerase-mediated genome-wide transcriptional responses in Escherichia coli
por: Reckinger, Amy R., et al.
Publicado: (2007)

Rad51 and RecA juxtapose dsDNA ends ready for DNA ligase-catalyzed end-joining under recombinase-suppressive conditions
por: Konomura, Naoto, et al.
Publicado: (2017)

A RecB-family nuclease motif in the Type I restriction endonuclease EcoR124I
por: Šišáková, Eva, et al.
Publicado: (2008)

RecF protein targeting to post-replication (daughter strand) gaps II: RecF interaction with replisomes
por: Henry, Camille, et al.
Publicado: (2023)

Programmable cleavage of linear double-stranded DNA by combined action of Argonaute CbAgo from Clostridium butyricum and nuclease deficient RecBC helicase from E. coli
por: Vaiskunaite, Rita, et al.
Publicado: (2022)

Mechanism of RecQ helicase mechanoenzymatic coupling reveals that the DNA interactions of the ADP-bound enzyme control translocation run terminations
por: Sarlós, Kata, et al.
Publicado: (2015)

An Mrr-family nuclease motif in the single polypeptide restriction–modification enzyme LlaGI
por: Smith, Rachel M., et al.
Publicado: (2009)

Coordinate 5′ and 3′ endonucleolytic trimming of terminally blocked blunt DNA double-strand break ends by Artemis nuclease and DNA-dependent protein kinase
por: Yannone, Steven M., et al.
Publicado: (2008)

Participation of RecJ in the base excision repair pathway of Deinococcus radiodurans
por: Cheng, Kaiying, et al.
Publicado: (2020)

RecG interacts directly with SSB: implications for stalled replication fork regression
por: Buss, Jackson A., et al.
Publicado: (2008)

Nanopore tweezers measurements of RecQ conformational changes reveal the energy landscape of helicase motion
por: Craig, Jonathan M, et al.
Publicado: (2022)

Tetrameric restriction enzymes: expansion to the GIY-YIG nuclease family
por: Gasiunas, Giedrius, et al.
Publicado: (2008)

A novel DNA nuclease is stimulated by association with the GINS complex
por: Li, Zhuo, et al.
Publicado: (2011)

Autonomous zinc-finger nuclease pairs for targeted chromosomal deletion
por: Şöllü, Cem, et al.
Publicado: (2010)

Sequence-dependent nanometer-scale conformational dynamics of individual RecBCD–DNA complexes
por: Carter, Ashley R., et al.
Publicado: (2016)

Mb- and FnCpf1 nucleases are active in mammalian cells: activities and PAM preferences of four wild-type Cpf1 nucleases and of their altered PAM specificity variants
por: Tóth, Eszter, et al.
Publicado: (2018)

megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering
por: Boissel, Sandrine, et al.
Publicado: (2014)

Dimerization of SLX4 contributes to functioning of the SLX4-nuclease complex
por: Yin, Jinhu, et al.
Publicado: (2016)

The RecQ helicase Sgs1 drives ATP-dependent disruption of Rad51 filaments
por: Crickard, J Brooks, et al.
Publicado: (2019)

Efficient processing of TFO-directed psoralen DNA interstrand crosslinks by the UvrABC nuclease
por: Christensen, Laura A., et al.
Publicado: (2008)

Argonaute of the archaeon Pyrococcus furiosus is a DNA-guided nuclease that targets cognate DNA
por: Swarts, Daan C., et al.
Publicado: (2015)

Regulation by interdomain communication of a headful packaging nuclease from bacteriophage T4
por: Ghosh-Kumar, Manjira, et al.
Publicado: (2011)

Dna2 is a structure-specific nuclease, with affinity for 5′-flap intermediates
por: Stewart, Jason A., et al.
Publicado: (2010)

The nuclease domain of the SPP1 packaging motor coordinates DNA cleavage and encapsidation
por: Cornilleau, Charlène, et al.
Publicado: (2013)

A programmable omnipotent Argonaute nuclease from mesophilic bacteria Kurthia massiliensis
por: Liu, Yang, et al.
Publicado: (2021)

Bacterial Argonaute nucleases reveal different modes of DNA targeting in vitro and in vivo
por: Lisitskaya, Lidiya, et al.
Publicado: (2023)

Type III restriction endonucleases are heterotrimeric: comprising one helicase–nuclease subunit and a dimeric methyltransferase that binds only one specific DNA
por: Butterer, Annika, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_givd298hib7jpvm6gjrhj8visb