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Detection of recurrent alternative splicing switches in tumor samples reveals novel signatures of cancer
The determination of the alternative splicing isoforms expressed in cancer is fundamental for the development of tumor-specific molecular targets for prognosis and therapy, but it is hindered by the heterogeneity of tumors and the variability across patients. We developed a new computational method,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330360/ https://www.ncbi.nlm.nih.gov/pubmed/25578962 http://dx.doi.org/10.1093/nar/gku1392 |