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Detection of recurrent alternative splicing switches in tumor samples reveals novel signatures of cancer

The determination of the alternative splicing isoforms expressed in cancer is fundamental for the development of tumor-specific molecular targets for prognosis and therapy, but it is hindered by the heterogeneity of tumors and the variability across patients. We developed a new computational method,...

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Detalles Bibliográficos
Autores principales: Sebestyén, Endre, Zawisza, Michał, Eyras, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330360/
https://www.ncbi.nlm.nih.gov/pubmed/25578962
http://dx.doi.org/10.1093/nar/gku1392