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53BP1 promotes microhomology-mediated end-joining in G1-phase cells

Alternative non-homologous end joining (alt-NHEJ) was originally identified as a backup repair mechanism in the absence of classical NHEJ (c-NHEJ) factors but recent studies have demonstrated that alt-NHEJ is active even when c-NHEJ as well as homologous recombination is available. The functions of...

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Detalles Bibliográficos
Autores principales: Xiong, Xiahui, Du, Zhanwen, Wang, Ying, Feng, Zhihui, Fan, Pan, Yan, Chunhong, Willers, Henning, Zhang, Junran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330367/
https://www.ncbi.nlm.nih.gov/pubmed/25586219
http://dx.doi.org/10.1093/nar/gku1406