The Krüppel-associated box repressor domain induces reversible and irreversible regulation of endogenous mouse genes by mediating different chromatin states

The Krüppel-associated box (KRAB) domain is a transcription repression module from the largest family of transcriptional regulators encoded by higher vertebrates. We developed a drug-controllable regulation system based on an artificial KRAB-containing repressor (tTS) that targets the endogenous Hpr...

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Detalles Bibliográficos
Autores principales: Ying, Yue, Yang, Xingyu, Zhao, Kai, Mao, Jifang, Kuang, Ying, Wang, Zhugang, Sun, Ruilin, Fei, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330378/
https://www.ncbi.nlm.nih.gov/pubmed/25609696
http://dx.doi.org/10.1093/nar/gkv016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330378/
https://www.ncbi.nlm.nih.gov/pubmed/25609696
http://dx.doi.org/10.1093/nar/gkv016

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