Evaluating the potential for undesired genomic effects of the piggyBac transposon system in human cells

Non-viral transposons have been used successfully for genetic modification of clinically relevant cells including embryonic stem, induced pluripotent stem, hematopoietic stem and primary human T cell types. However, there has been limited evaluation of undesired genomic effects when using transposon...

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Detalles Bibliográficos
Autores principales: Saha, Sunandan, Woodard, Lauren E., Charron, Elizabeth M., Welch, Richard C., Rooney, Cliona M., Wilson, Matthew H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330379/
https://www.ncbi.nlm.nih.gov/pubmed/25605795
http://dx.doi.org/10.1093/nar/gkv017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330379/
https://www.ncbi.nlm.nih.gov/pubmed/25605795
http://dx.doi.org/10.1093/nar/gkv017

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