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Evaluating the potential for undesired genomic effects of the piggyBac transposon system in human cells
Non-viral transposons have been used successfully for genetic modification of clinically relevant cells including embryonic stem, induced pluripotent stem, hematopoietic stem and primary human T cell types. However, there has been limited evaluation of undesired genomic effects when using transposon...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330379/ https://www.ncbi.nlm.nih.gov/pubmed/25605795 http://dx.doi.org/10.1093/nar/gkv017 |