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Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells

Endothelial cells are important elements in the vascular response to danger-associated molecules signaling through toll-like receptors (TLRs). Flotillin-1 and -2 are markers of membrane rafts but their true endothelial function is unknown. We hypothesized that flotillins are required for TLR signali...

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Detalles Bibliográficos
Autores principales: Fork, Christian, Hitzel, Juliane, Nichols, Benjamin J., Tikkanen, Ritva, Brandes, Ralf P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330457/
https://www.ncbi.nlm.nih.gov/pubmed/25204797
http://dx.doi.org/10.1007/s00395-014-0439-4