Application of IL-36 receptor antagonist weakens CCL20 expression and impairs recovery in the late phase of murine acetaminophen-induced liver injury

Overdosing of the analgesic acetaminophen (APAP, paracetamol) is a major cause of acute liver injury. Whereas toxicity is initiated by hepatocyte necrosis, course of disease is regulated by mechanisms of innate immunity having the potential to serve in complex manner pathogenic or pro-regenerative f...

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Detalles Bibliográficos
Autores principales: Scheiermann, Patrick, Bachmann, Malte, Härdle, Lorena, Pleli, Thomas, Piiper, Albrecht, Zwissler, Bernhard, Pfeilschifter, Josef, Mühl, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330543/
https://www.ncbi.nlm.nih.gov/pubmed/25687687
http://dx.doi.org/10.1038/srep08521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330543/
https://www.ncbi.nlm.nih.gov/pubmed/25687687
http://dx.doi.org/10.1038/srep08521

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