Structural and dynamic properties that govern the stability of an engineered fibronectin type III domain

Consensus protein design is a rapid and reliable technique for the improvement of protein stability, which relies on the use of homologous protein sequences. To enhance the stability of a fibronectin type III (FN3) domain, consensus design was employed using an alignment of 2123 sequences. The resul...

Descripción completa

Detalles Bibliográficos
Autores principales: Porebski, Benjamin T., Nickson, Adrian A., Hoke, David E., Hunter, Morag R., Zhu, Liguang, McGowan, Sheena, Webb, Geoffrey I., Buckle, Ashley M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330816/
https://www.ncbi.nlm.nih.gov/pubmed/25691761
http://dx.doi.org/10.1093/protein/gzv002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330816/
https://www.ncbi.nlm.nih.gov/pubmed/25691761
http://dx.doi.org/10.1093/protein/gzv002

Ejemplares similares