Advanced Glycation End Products Induce Endothelial-to-Mesenchymal Transition via Downregulating Sirt 1 and Upregulating TGF-β in Human Endothelial Cells

In the present study, we examined the advanced glycation end products- (AGEs-) induced endothelial-to-mesenchymal transition (EndMT) in human umbilical vein endothelial cells (HUVECs). Results demonstrated that AGE-BSAs significantly reduced the cluster of differentiation 31 (CD 31) expression, wher...

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Detalles Bibliográficos
Autores principales: He, Wei, Zhang, Jian, Gan, Tian-yi, Xu, Guo-jun, Tang, Bao-peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330956/
https://www.ncbi.nlm.nih.gov/pubmed/25710021
http://dx.doi.org/10.1155/2015/684242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330956/
https://www.ncbi.nlm.nih.gov/pubmed/25710021
http://dx.doi.org/10.1155/2015/684242

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