A Tetrahymena Hsp90 co-chaperone promotes siRNA loading by ATP-dependent and ATP-independent mechanisms

The loading of small interfering RNAs (siRNAs) and microRNAs into Argonaute proteins is enhanced by Hsp90 and ATP in diverse eukaryotes. However, whether this loading also occurs independently of Hsp90 and ATP remains unclear. We show that the Tetrahymena Hsp90 co-chaperone Coi12p promotes siRNA loa...

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Detalles Bibliográficos
Autores principales: Woehrer, Sophie L, Aronica, Lucia, Suhren, Jan H, Busch, Clara Jana-Lui, Noto, Tomoko, Mochizuki, Kazufumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331008/
https://www.ncbi.nlm.nih.gov/pubmed/25588944
http://dx.doi.org/10.15252/embj.201490062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331008/
https://www.ncbi.nlm.nih.gov/pubmed/25588944
http://dx.doi.org/10.15252/embj.201490062

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