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Establishment of a Patient-Derived Orthotopic Xenograft (PDOX) Model of HER-2-Positive Cervical Cancer Expressing the Clinical Metastatic Pattern

Squamous cell carcinoma of the cervix, highly prevalent in the developing world, is often metastatic and treatment resistant with no standard treatment protocol. Our laboratory pioneered the patient-derived orthotopic xenograft (PDOX) nude mouse model with the technique of surgical orthotopic implan...

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Detalles Bibliográficos
Autores principales: Hiroshima, Yukihiko, Zhang, Yong, Zhang, Nan, Maawy, Ali, Mii, Sumiyuki, Yamamoto, Mako, Uehara, Fuminari, Miwa, Shinji, Yano, Shuya, Murakami, Takashi, Momiyama, Masashi, Chishima, Takashi, Tanaka, Kuniya, Ichikawa, Yasushi, Bouvet, Michael, Murata, Takuya, Endo, Itaru, Hoffman, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331082/
https://www.ncbi.nlm.nih.gov/pubmed/25689852
http://dx.doi.org/10.1371/journal.pone.0117417