Cargando…

Establishment of a Patient-Derived Orthotopic Xenograft (PDOX) Model of HER-2-Positive Cervical Cancer Expressing the Clinical Metastatic Pattern

Squamous cell carcinoma of the cervix, highly prevalent in the developing world, is often metastatic and treatment resistant with no standard treatment protocol. Our laboratory pioneered the patient-derived orthotopic xenograft (PDOX) nude mouse model with the technique of surgical orthotopic implan...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hiroshima, Yukihiko, Zhang, Yong, Zhang, Nan, Maawy, Ali, Mii, Sumiyuki, Yamamoto, Mako, Uehara, Fuminari, Miwa, Shinji, Yano, Shuya, Murakami, Takashi, Momiyama, Masashi, Chishima, Takashi, Tanaka, Kuniya, Ichikawa, Yasushi, Bouvet, Michael, Murata, Takuya, Endo, Itaru, Hoffman, Robert M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331082/ https://www.ncbi.nlm.nih.gov/pubmed/25689852 http://dx.doi.org/10.1371/journal.pone.0117417

Ejemplares similares

Efficacy of tumor-targeting Salmonella typhimurium A1-R in combination with anti-angiogenesis therapy on a pancreatic cancer patient-derived orthotopic xenograft (PDOX) and cell line mouse models
por: Hiroshima, Yukihiko, et al.
Publicado: (2014)

Fluorescence-Guided Surgery in Combination with UVC Irradiation Cures Metastatic Human Pancreatic Cancer in Orthotopic Mouse Models
por: Hiroshima, Yukihiko, et al.
Publicado: (2014)

Tumor-Targeting Salmonella typhimurium A1-R in Combination with Trastuzumab Eradicates HER-2-Positive Cervical Cancer Cells in Patient-Derived Mouse Models
por: Hiroshima, Yukihiko, et al.
Publicado: (2015)

Tumor-Targeting Salmonella typhimurium A1-R Arrests a Chemo-Resistant Patient Soft-Tissue Sarcoma in Nude Mice
por: Hiroshima, Yukihiko, et al.
Publicado: (2015)

Metastatic Recurrence in a Pancreatic Cancer Patient Derived Orthotopic Xenograft (PDOX) Nude Mouse Model Is Inhibited by Neoadjuvant Chemotherapy in Combination with Fluorescence-Guided Surgery with an Anti-CA 19-9-Conjugated Fluorophore
por: Hiroshima, Yukihiko, et al.
Publicado: (2014)

The Tumor-Educated-Macrophage Increase of Malignancy of Human Pancreatic Cancer Is Prevented by Zoledronic Acid
por: Hiroshima, Yukihiko, et al.
Publicado: (2014)

Color-coding cancer and stromal cells with genetic reporters in a patient-derived orthotopic xenograft (PDOX) model of pancreatic cancer enhances fluorescence-guided surgery
por: Yano, Shuya, et al.
Publicado: (2015)

Patient-derived mouse models of cancer need to be orthotopic in order to evaluate targeted anti-metastatic therapy
por: Hiroshima, Yukihiko, et al.
Publicado: (2016)

Tumor-targeting Salmonella typhimurium A1-R in combination with doxorubicin eradicate soft tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) model
por: Murakami, Takashi, et al.
Publicado: (2016)

Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model
por: Murakami, Takashi, et al.
Publicado: (2017)

Fluorescence-Guided Surgery of Liver Metastasis in Orthotopic Nude-Mouse Models
por: Murakami, Takashi, et al.
Publicado: (2015)

Efficacy of Tumor-Targeting Salmonella A1-R on a Melanoma Patient-Derived Orthotopic Xenograft (PDOX) Nude-Mouse Model
por: Yamamoto, Mako, et al.
Publicado: (2016)

Efficacy of Tumor-Targeting Salmonella typhimurium A1-R against Malignancies in Patient-Derived Orthotopic Xenograft (PDOX) Murine Models
por: Murakami, Takashi, et al.
Publicado: (2019)

Therapeutic efficacy of tumor-targeting Salmonella typhimurium A1-R on human colorectal cancer liver metastasis in orthotopic nude-mouse models
por: Murakami, Takashi, et al.
Publicado: (2015)

Adjuvant treatment with tumor-targeting Salmonella typhimurium A1-R reduces recurrence and increases survival after liver metastasis resection in an orthotopic nude mouse model
por: Murakami, Takashi, et al.
Publicado: (2015)

The combination of temozolomide-irinotecan regresses a doxorubicin-resistant patient-derived orthotopic xenograft (PDOX) nude-mouse model of recurrent Ewing’s sarcoma with a FUS-ERG fusion and CDKN2A deletion: Direction for third-line patient therapy
por: Miyake, Kentaro, et al.
Publicado: (2017)

Effective molecular targeting of CDK4/6 and IGF-1R in a rare FUS-ERG fusion CDKN2A-deletion doxorubicin-resistant Ewing's sarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model
por: Murakami, Takashi, et al.
Publicado: (2016)

Nestin-Expressing Stem Cells Promote Nerve Growth in Long-Term 3-Dimensional Gelfoam®-Supported Histoculture
por: Mii, Sumiyuki, et al.
Publicado: (2013)

Patient-Derived Orthotopic Xenograft (PDOX) Models of Melanoma †
por: Hoffman, Robert M.
Publicado: (2017)

MEK inhibitors cobimetinib and trametinib, regressed a gemcitabine-resistant pancreatic-cancer patient-derived orthotopic xenograft (PDOX)
por: Kawaguchi, Kei, et al.
Publicado: (2017)

Fluorescence-Guided Surgery of Retroperitoneal-Implanted Human Fibrosarcoma in Nude Mice Delays or Eliminates Tumor Recurrence and Increases Survival Compared to Bright-Light Surgery
por: Uehara, Fuminari, et al.
Publicado: (2015)

Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models of Primary and Recurrent Meningioma
por: Zhang, Huiyuan, et al.
Publicado: (2020)

Targeting tumors with a killer-reporter adenovirus for curative fluorescence-guided surgery of soft-tissue sarcoma
por: Yano, Shuya, et al.
Publicado: (2015)

Intraperitoneal administration of tumor-targeting Salmonella typhimurium A1-R inhibits disseminated human ovarian cancer and extends survival in nude mice
por: Matsumoto, Yasunori, et al.
Publicado: (2015)

Review: Precise sarcoma patient-derived orthotopic xenograft (PDOX) mouse models enable identification of novel effective combination therapies with the cyclin-dependent kinase inhibitor palbociclib: A strategy for clinical application
por: Higuchi, Takashi, et al.
Publicado: (2022)

MUC1 Selectively Targets Human Pancreatic Cancer in Orthotopic Nude Mouse Models
por: Park, Jeong Youp, et al.
Publicado: (2015)

Temozolomide combined with irinotecan caused regression in an adult pleomorphic rhabdomyosarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model
por: Igarashi, Kentaro, et al.
Publicado: (2017)

Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model
por: Lwin, Thinzar M., et al.
Publicado: (2018)

Improved Resection and Outcome of Colon-Cancer Liver Metastasis with Fluorescence-Guided Surgery Using In Situ GFP Labeling with a Telomerase-Dependent Adenovirus in an Orthotopic Mouse Model
por: Yano, Shuya, et al.
Publicado: (2016)

Tumor-targeting Salmonella typhimurium A1-R prevents experimental human breast cancer bone metastasis in nude mice
por: Miwa, Shinji, et al.
Publicado: (2014)

Efficacy of Recombinant Methioninase (rMETase) on Recalcitrant Cancer Patient-Derived Orthotopic Xenograft (PDOX) Mouse Models: A Review
por: Kawaguchi, Kei, et al.
Publicado: (2019)

Inhibition of spontaneous and experimental lung metastasis of soft-tissue sarcoma by tumor-targeting Salmonella typhimurium A1-R
por: Miwa, Shinji, et al.
Publicado: (2014)

Patient-derived orthotopic xenograft models for cancer of unknown primary precisely distinguish chemotherapy, and tumor-targeting S. typhimurium A1-R is superior to first-line chemotherapy
por: Miyake, Kentaro, et al.
Publicado: (2018)

Trabectedin arrests a doxorubicin-resistant PDGFRA-activated liposarcoma patient-derived orthotopic xenograft (PDOX) nude mouse model
por: Kiyuna, Tasuku, et al.
Publicado: (2018)

Recombinant methioninase combined with doxorubicin (DOX) regresses a DOX-resistant synovial sarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model
por: Igarashi, Kentaro, et al.
Publicado: (2018)

A novel patient-derived orthotopic xenograft (PDOX) mouse model of highly-aggressive liver metastasis for identification of candidate effective drug-combinations
por: Zhang, Zhiying, et al.
Publicado: (2020)

A novel anionic-phosphate-platinum complex effectively targets an undifferentiated pleomorphic sarcoma better than cisplatinum and doxorubicin in a patient-derived orthotopic xenograft (PDOX)
por: Igarashi, Kentaro, et al.
Publicado: (2017)

High efficacy of tumor-targeting Salmonella typhimurium A1-R on a doxorubicin- and dactolisib-resistant follicular dendritic-cell sarcoma in a patient-derived orthotopic xenograft PDOX nude mouse model
por: Kiyuna, Tasuku, et al.
Publicado: (2016)

Temozolomide combined with irinotecan regresses a cisplatinum-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) precision-oncology mouse model
por: Igarashi, Kentaro, et al.
Publicado: (2017)

A patient-derived orthotopic xenograft (PDOX) mouse model of a cisplatinum-resistant osteosarcoma lung metastasis that was sensitive to temozolomide and trabectedin: implications for precision oncology
por: Igarashi, Kentaro, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ddskn593n4jbe9fbt96pb12v8u