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Preventing Effect of L-Type Calcium Channel Blockade on Electrophysiological Alterations in Dentate Gyrus Granule Cells Induced by Entorhinal Amyloid Pathology

The entorhinal cortex (EC) is one of the earliest affected brain regions in Alzheimer’s disease (AD). EC-amyloid pathology induces synaptic failure in the dentate gyrus (DG) with resultant behavioral impairment, but there is little known about its impact on neuronal properties in the DG. It is belie...

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Detalles Bibliográficos
Autores principales: Pourbadie, Hamid Gholami, Naderi, Nima, Mehranfard, Nasrin, Janahmadi, Mahyar, Khodagholi, Fariba, Motamedi, Fereshteh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331091/
https://www.ncbi.nlm.nih.gov/pubmed/25689857
http://dx.doi.org/10.1371/journal.pone.0117555