The relative magnitude of transgene-specific adaptive immune responses induced by human and chimpanzee adenovirus vectors differs between laboratory animals and a target species

Adenovirus vaccine vectors generated from new viral serotypes are routinely screened in pre-clinical laboratory animal models to identify the most immunogenic and efficacious candidates for further evaluation in clinical human and veterinary settings. Here, we show that studies in a laboratory speci...

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Detalles Bibliográficos
Autores principales: Dicks, Matthew D.J., Guzman, Efrain, Spencer, Alexandra J., Gilbert, Sarah C., Charleston, Bryan, Hill, Adrian V.S., Cottingham, Matthew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331283/
https://www.ncbi.nlm.nih.gov/pubmed/25629523
http://dx.doi.org/10.1016/j.vaccine.2015.01.042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331283/
https://www.ncbi.nlm.nih.gov/pubmed/25629523
http://dx.doi.org/10.1016/j.vaccine.2015.01.042

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