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Erythropoietin and organ protection: lessons from negative clinical trials
Based on its pleiotropic effects, erythropoietin can decrease inflammation, oxidative stress, and apoptosis. Erythropoietin provides organ protection for the heart, brain, and kidney in diverse preclinical animal studies, especially models that include ischemia–reperfusion injury and/or inflammation...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331307/ https://www.ncbi.nlm.nih.gov/pubmed/25672222 http://dx.doi.org/10.1186/s13054-014-0526-9 |