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OVCAR-3 Spheroid-Derived Cells Display Distinct Metabolic Profiles

INTRODUCTION: Recently, multicellular spheroids were isolated from a well-established epithelial ovarian cancer cell line, OVCAR-3, and were propagated in vitro. These spheroid-derived cells displayed numerous hallmarks of cancer stem cells, which are chemo- and radioresistant cells thought to be a...

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Detalles Bibliográficos
Autores principales: Vermeersch, Kathleen A., Wang, Lijuan, Mezencev, Roman, McDonald, John F., Styczynski, Mark P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331360/
https://www.ncbi.nlm.nih.gov/pubmed/25688563
http://dx.doi.org/10.1371/journal.pone.0118262