A novel adenoviral vector carrying an all-in-one Tet-On system with an autoregulatory loop for tight, inducible transgene expression

BACKGROUND: One of the most commonly used vectors for gene therapy is the adenoviral vector; its ability to tightly regulate transgene expression is critical for optimizing therapeutic outcomes. The tetracycline-regulated system (especially the Tet-On system) for gene expression is one of the most v...

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Detalles Bibliográficos
Autores principales: Chen, Hao, Wang, Dongyang, Xia, Ruiting, Mao, Qinwen, Xia, Haibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331377/
https://www.ncbi.nlm.nih.gov/pubmed/25888000
http://dx.doi.org/10.1186/s12896-015-0121-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331377/
https://www.ncbi.nlm.nih.gov/pubmed/25888000
http://dx.doi.org/10.1186/s12896-015-0121-4

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