Engineering Isoprenoid Biosynthesis in Artemisia annua L. for the Production of Taxadiene: A Key Intermediate of Taxol

Taxadiene is the first committed precursor to paclitaxel, marketed as Taxol, arguably the most important anticancer agent against ovarian and breast cancer. In Taxus, taxadiene is directly synthesized from geranylgeranyl diphosphate (GGPP) that is the common precursor for diterpenoids and is found i...

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Detalles Bibliográficos
Autores principales: Li, Meiya, Jiang, Fusheng, Yu, Xiangli, Miao, Zhiqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331392/
https://www.ncbi.nlm.nih.gov/pubmed/25705665
http://dx.doi.org/10.1155/2015/504932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331392/
https://www.ncbi.nlm.nih.gov/pubmed/25705665
http://dx.doi.org/10.1155/2015/504932

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