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Classification of Beta-Lactamases and Penicillin Binding Proteins Using Ligand-Centric Network Models
β-lactamase mediated antibiotic resistance is an important health issue and the discovery of new β-lactam type antibiotics or β-lactamase inhibitors is an area of intense research. Today, there are about a thousand β-lactamases due to the evolutionary pressure exerted by these ligands. While β-lacta...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331424/ https://www.ncbi.nlm.nih.gov/pubmed/25689853 http://dx.doi.org/10.1371/journal.pone.0117874 |