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Conserved Surface Accessible Nucleoside ABC Transporter Component SP0845 Is Essential for Pneumococcal Virulence and Confers Protection In Vivo

Streptococcus pneumoniae is a leading cause of bacterial pneumonia, sepsis and meningitis. Surface accessible proteins of S. pneumoniae are being explored for the development of a protein-based vaccine in order to overcome the limitations of existing polysaccharide-based pneumococcal vaccines. To id...

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Detalles Bibliográficos
Autores principales: Saxena, Sneha, Khan, Naeem, Dehinwal, Ruchika, Kumar, Ajay, Sehgal, Devinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331430/
https://www.ncbi.nlm.nih.gov/pubmed/25689507
http://dx.doi.org/10.1371/journal.pone.0118154