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The Gastrointestinal Irritation of Polygala Saponins and Its Potential Mechanism In Vitro and In Vivo

Processing alters the pharmacological activity and reduces the gastrointestinal toxicity of the polygalae. To investigate the effect of processing, different glycosyl substituent products were tested. Hypnotic and subhypnotic doses of pentobarbital-induced sleep tests on mice were used to evaluate t...

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Detalles Bibliográficos
Autores principales: Wen, Li, Xia, Nan, Tang, PeiPei, Hong, Yi, Wang, ZiZhen, Liu, YaJie, Liu, YanJu, Liu, JianJun, Li, XiangQiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331466/
https://www.ncbi.nlm.nih.gov/pubmed/25705699
http://dx.doi.org/10.1155/2015/918048