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Characterization of tissue-specific differential DNA methylation suggests distinct modes of positive and negative gene expression regulation

BACKGROUND: DNA methylation plays an important role in regulating gene expression during many biological processes. However, the mechanism of DNA-methylation-dependent gene regulation is not fully understood. Here, we explore two possible DNA methylation regulatory mechanisms with opposite modes of...

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Detalles Bibliográficos
Autores principales: Wan, Jun, Oliver, Verity F, Wang, Guohua, Zhu, Heng, Zack, Donald J, Merbs, Shannath L, Qian, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331481/
https://www.ncbi.nlm.nih.gov/pubmed/25652663
http://dx.doi.org/10.1186/s12864-015-1271-4