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Characterization of tissue-specific differential DNA methylation suggests distinct modes of positive and negative gene expression regulation
BACKGROUND: DNA methylation plays an important role in regulating gene expression during many biological processes. However, the mechanism of DNA-methylation-dependent gene regulation is not fully understood. Here, we explore two possible DNA methylation regulatory mechanisms with opposite modes of...
Autores principales: | Wan, Jun, Oliver, Verity F, Wang, Guohua, Zhu, Heng, Zack, Donald J, Merbs, Shannath L, Qian, Jiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331481/ https://www.ncbi.nlm.nih.gov/pubmed/25652663 http://dx.doi.org/10.1186/s12864-015-1271-4 |
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