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Modeling Chemotherapeutic Neurotoxicity with Human Induced Pluripotent Stem Cell-Derived Neuronal Cells

There are no effective agents to prevent or treat chemotherapy-induced peripheral neuropathy (CIPN), the most common non-hematologic toxicity of chemotherapy. Therefore, we sought to evaluate the utility of human neuron-like cells derived from induced pluripotent stem cells (iPSCs) as a means to stu...

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Detalles Bibliográficos
Autores principales: Wheeler, Heather E., Wing, Claudia, Delaney, Shannon M., Komatsu, Masaaki, Dolan, M. Eileen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331516/
https://www.ncbi.nlm.nih.gov/pubmed/25689802
http://dx.doi.org/10.1371/journal.pone.0118020