Cargando…

Modeling Chemotherapeutic Neurotoxicity with Human Induced Pluripotent Stem Cell-Derived Neuronal Cells

There are no effective agents to prevent or treat chemotherapy-induced peripheral neuropathy (CIPN), the most common non-hematologic toxicity of chemotherapy. Therefore, we sought to evaluate the utility of human neuron-like cells derived from induced pluripotent stem cells (iPSCs) as a means to stu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wheeler, Heather E., Wing, Claudia, Delaney, Shannon M., Komatsu, Masaaki, Dolan, M. Eileen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331516/ https://www.ncbi.nlm.nih.gov/pubmed/25689802 http://dx.doi.org/10.1371/journal.pone.0118020

Ejemplares similares

Pluripotent Stem Cell-derived Dopaminergic Neurons for Studying Developmental Neurotoxicity
por: Kreutz, Anna, et al.
Publicado: (2023)

Human Induced Pluripotent Stem Cell Derived Sensory Neurons are Sensitive to the Neurotoxic Effects of Paclitaxel
por: Xiong, Chenling, et al.
Publicado: (2020)

Dataset for: Modeling chemotherapy induced neurotoxicity with human induced pluripotent stem cell (iPSC)-derived sensory neurons
por: Schinke, Christian, et al.
Publicado: (2021)

Neuroprotective efficacy of thymoquinone against amyloid beta-induced neurotoxicity in human induced pluripotent stem cell-derived cholinergic neurons
por: Alhibshi, A.H., et al.
Publicado: (2019)

Protocol for the Differentiation of Human Induced Pluripotent Stem Cells into Mixed Cultures of Neurons and Glia for Neurotoxicity Testing
por: Pistollato, Francesca, et al.
Publicado: (2017)

Human Induced Pluripotent Stem Cell-Derived 3D-Neurospheres Are Suitable for Neurotoxicity Screening
por: Kobolak, Julianna, et al.
Publicado: (2020)

Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons
por: Chuang, Wenpo, et al.
Publicado: (2017)

Intrinsically Active and Pacemaker Neurons in Pluripotent Stem Cell-Derived Neuronal Populations
por: Illes, Sebastian, et al.
Publicado: (2014)

Transgene Reactivation in Induced Pluripotent Stem Cell Derivatives and Reversion to Pluripotency of Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells
por: Galat, Vasiliy, et al.
Publicado: (2016)

Pharmacogenomics of chemotherapeutic susceptibility and toxicity
por: Moen, Erika L, et al.
Publicado: (2012)

Characterization of Induced Pluripotent Stem Cell-derived Human Serotonergic Neurons
por: Cao, Lining, et al.
Publicado: (2017)

Genome-Wide Local Ancestry Approach Identifies Genes and Variants Associated with Chemotherapeutic Susceptibility in African Americans
por: Wheeler, Heather E., et al.
Publicado: (2011)

Modeling alcohol-induced neurotoxicity using human induced pluripotent stem cell-derived three-dimensional cerebral organoids
por: Arzua, Thiago, et al.
Publicado: (2020)

Disrupted neuronal maturation in Angelman syndrome-derived induced pluripotent stem cells
por: Fink, James J., et al.
Publicado: (2017)

An induced pluripotent stem cell-based model identifies molecular targets of vincristine neurotoxicity
por: Tsai, Neng-Wei, et al.
Publicado: (2022)

Transferable neuronal mini-cultures to accelerate screening in primary and induced pluripotent stem cell-derived neurons
por: Niedringhaus, Mark, et al.
Publicado: (2015)

Early‐stage development of human induced pluripotent stem cell‐derived neurons
por: Ohara, Yuki, et al.
Publicado: (2015)

Using induced pluripotent stem cells derived neurons to model brain diseases
por: McKinney, Cindy E.
Publicado: (2017)

Protocol for morphometric analysis of neurons derived from human pluripotent stem cells
por: Mucci, Sofía, et al.
Publicado: (2022)

Isolation of human pluripotent stem cell-derived sensory neuron subtypes by immunopanning
por: Saito-Diaz, Kenyi, et al.
Publicado: (2023)

Correction to: Modeling alcohol-induced neurotoxicity using human induced pluripotent stem cell-derived three-dimensional cerebral organoids
por: Arzua, Thiago, et al.
Publicado: (2021)

Maturation of Human Pluripotent Stem Cell-Derived Cerebellar Neurons in the Absence of Co-culture
por: Silva, Teresa P., et al.
Publicado: (2020)

Derivation and Identification of Motor Neurons from Human Urine-Derived Induced Pluripotent Stem Cells
por: Yi, Huan, et al.
Publicado: (2018)

Manifestation of Huntington’s disease pathology in human induced pluripotent stem cell-derived neurons
por: Nekrasov, Evgeny D., et al.
Publicado: (2016)

Innervation of Cochlear Hair Cells by Human Induced Pluripotent Stem Cell-Derived Neurons In Vitro
por: Gunewardene, Niliksha, et al.
Publicado: (2016)

Increased Neuronal Differentiation Efficiency in High Cell Density-Derived Induced Pluripotent Stem Cells
por: Srimasorn, Sumitra, et al.
Publicado: (2019)

A Comprehensive Analysis of Protocols for Deriving Dopaminergic Neurons from Human Pluripotent Stem Cells
por: Marton, Rebecca M., et al.
Publicado: (2018)

Tranylcypromine Causes Neurotoxicity and Represses BHC110/LSD1 in Human-Induced Pluripotent Stem Cell-Derived Cerebral Organoids Model
por: Huang, Jing, et al.
Publicado: (2017)

Protocol for measurement of calcium dysregulation in human induced pluripotent stem cell-derived dopaminergic neurons
por: Yin, Xiling, et al.
Publicado: (2021)

Ketamine Causes Mitochondrial Dysfunction in Human Induced Pluripotent Stem Cell-Derived Neurons
por: Ito, Hiroyuki, et al.
Publicado: (2015)

Deriving striatal projection neurons from human pluripotent stem cells with Activin A
por: Noakes, Zoe, et al.
Publicado: (2015)

Rett syndrome induced pluripotent stem cell-derived neurons reveal novel neurophysiological alterations
por: Farra, N, et al.
Publicado: (2012)

Deciphering the Proteome Dynamics during Development of Neurons Derived from Induced Pluripotent Stem Cells
por: Varderidou-Minasian, Suzy, et al.
Publicado: (2020)

Cellular and molecular characterization of multiplex autism in human induced pluripotent stem cell-derived neurons
por: Lewis, Emily M. A., et al.
Publicado: (2019)

Mitochondrial Abnormalities in Induced Pluripotent Stem Cells-Derived Motor Neurons from Patients with Riboflavin Transporter Deficiency
por: Colasuonno, Fiorella, et al.
Publicado: (2020)

Proteomic Alterations and Novel Markers of Neurotoxic Reactive Astrocytes in Human Induced Pluripotent Stem Cell Models
por: Labib, David, et al.
Publicado: (2022)

Enhanced derivation of human pluripotent stem cell-derived cortical glutamatergic neurons by a small molecule
por: Cao, Shi-Ying, et al.
Publicado: (2017)

Mitochondrial Dysfunction and Calcium Dysregulation in Leigh Syndrome Induced Pluripotent Stem Cell Derived Neurons
por: Galera-Monge, Teresa, et al.
Publicado: (2020)

Patient-Derived Colorectal Cancer Organoids Upregulate Revival Stem Cell Marker Genes Following Chemotherapeutic Treatment
por: Engel, Rebekah M., et al.
Publicado: (2020)

Genetic Correction of Tauopathy Phenotypes in Neurons Derived from Human Induced Pluripotent Stem Cells
por: Fong, Helen, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_lpbvvco0idtlqd2pngelva0jlv